Research & educational use only. This site catalogs
published research and public commentary about supplements and peptides.
It is not medical advice and not a recommendation to use any compound.
Consult a qualified clinician.
← Catalog BPC-157
peptide Regenerative PeptideRecovery & Tissue RepairGut & GI HealthAnti-inflammatory
A synthetic pentadecapeptide derived from a sequence in human gastric juice. Studied almost exclusively in animal and in-vitro models for tendon, ligament, muscle, and GI mucosal healing. Human clinical evidence is absent.
Synonyms
Body Protection Compound 157 · other BPC 157 · abbreviation PL 14736 · other Bepecin · brand
Synonyms drive on-site search and are used to index ingested research
papers and tweets to this page.
Safety
research only Not an approved drug or
dietary supplement. Cataloged for educational purposes only.
Contraindications
- Not approved for human use by the FDA or EMA
- No established human dosing, purity, or long-term safety data
Reported side effects
- Unknown in humans — human safety has not been characterized
BPC-157 is a research chemical. It is not an approved drug or dietary supplement. This page catalogs the research literature for educational purposes only and is explicitly not a recommendation for human use.
Protocols
| Goal | Route | Dose | Frequency | Timing | Cycle | Evidence |
|---|
| Reported systemic protocol (animal-derived, not human-validated) Animal models; no validated human protocol exists Dose ranges circulating in non-clinical communities are extrapolated from animal studies and are not supported by human trials.
| subcutaneous | 200–500 mcg | 1×/day | — | Continuous | preclinical |
Evidence — Reported systemic protocol (animal-derived, not human-validated)
Claims & evidence
Accelerates tendon-to-bone and ligament healing in rodent injury models.
Tendon / ligament repair positive preclinical
- paper supports The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration — Journal of Applied Physiology · 2011
- tweet mentions Peptides 101: What the most popular peptides do (and where to get them)
I get asked about peptides constantly, in person and online. Most people asking are confused. They don't know what peptides are, which ones are safe, how to use them, or where to get them. This article is a 101 explainer.
Caveats: This is not medical advice, nor a recommendation. The author runs Superpower and plans to launch peptides in the future. The author has personally used several of the peptides discussed; accounts of effects are subjective, not clinical.
What are peptides? A peptide is a chain of amino acids. There are millions of peptides already in the human body. DNA encodes RNA, which produces proteins and peptides that regulate biological functions. Insulin, Ozempic, and endorphins are all peptides. When people talk about peptides as a category they usually mean peptide pharmaceuticals injected to produce a positive effect.
To lose weight: semaglutide, tirzepatide, retatrutide. GLP-1 is released after eating and signals fullness but degrades in minutes; semaglutide is a long-acting synthetic GLP-1 (Ozempic/Wegovy), FDA-approved. Tirzepatide (Mounjaro/Zepbound) hits GLP-1 and GIP, FDA-approved and tested in tens of thousands. Retatrutide is the strongest cousin, not yet approved but with strong Phase 3 data, hitting GLP-1, GIP, and glucagon; the author microdoses it for focus because it eliminates food noise.
To put on muscle: CJC-1295, ipamorelin, sermorelin, tesamorelin. These signal the pituitary to release more growth hormone. CJC-1295 (GHRH mimic) and ipamorelin (ghrelin mimic) are stacked together. Sermorelin has decades of history in anti-aging/recovery clinics. Tesamorelin has one of the strongest evidence bases and is FDA-approved for HIV-related visceral fat loss.
To heal fast: BPC-157 and TB-500. BPC-157 appears in gastric secretions and speeds repair by supporting blood flow; mechanism plausible, animal data strong, human data thin. TB-500 is synthetic thymosin beta-4, works on tissue repair through a different pathway, and is almost always paired with BPC-157; same evidence pattern.
To have glowing skin: GHK-Cu, a copper-binding peptide for collagen, skin repair, wound healing, and potentially hair density; huge in skincare and looksmaxxing communities.
To be smarter: semax and selank, Russian brain peptides used for focus and calmness, taken as injectables or nasal spray.
To increase energy: MOTS-c and SS-31, which target mitochondria; popular with longevity researchers, science still early.
To sleep better & live longer: epitalon (four amino acids, studied for telomere length, longevity and sleep) and pinealon (three amino acids, studied for cognitive function and neuroprotection), from Russian pineal-gland research; most research from one group, long-term safety thin.
To not get sick: thymosin alpha-1, which regulates and strengthens the immune system and has a surprisingly deep clinical research history in infection, inflammation, and immune dysfunction.
How to use peptides (not medical advice): start with a well-researched peptide like GLP-1s; get bloodwork before and during; work with a doctor who knows the space; start low, go slow. Where to get them: prescription via pharmacy; compounding-legal sites like Ageless RX or Maximus; experimental peptides are sourced from Research Use Only sites, though the safe approach is to wait for FDA-legalized compounding. The peptide era is just getting started. — @maxmarchione
Protects gastrointestinal mucosa and promotes ulcer healing in animal models.
GI mucosal protection positive preclinical
No indexed research or commentary linked yet.
Efficacy and safety in humans.
Human outcomes inconclusive anecdotal
No indexed research or commentary linked yet.
Notes
Overview
BPC-157’s regenerative effects are reported consistently across preclinical
studies, but the absence of human trials means efficacy, dosing, and safety
in people remain unknown.
Research-only notice
This entry exists to organize the scientific literature. It is not medical
advice and not an endorsement of human use.