Overview
Glycinate chelation improves tolerability relative to inorganic magnesium salts, making it a common choice for daily repletion and evening use.
See the structured protocol table and cited research below.
Research & educational use only. This site catalogs
published research and public commentary about supplements and peptides.
It is not medical advice and not a recommendation to use any compound.
Consult a qualified clinician.
← Catalog Magnesium Glycinate
supplement MineralSleep & Circadian
A chelated form of magnesium bound to the amino acid glycine, chosen for good bioavailability and low GI laxative effect. Studied for repletion of magnesium status and, more tentatively, sleep quality.
Synonyms
Magnesium bisglycinate · chemical Magnesium diglycinate · chemical Mg glycinate · abbreviation 14783-68-7 · cas
Synonyms drive on-site search and are used to index ingested research papers and tweets to this page.
Safety
Contraindications
- Significant renal impairment (risk of hypermagnesemia — consult a clinician)
Reported side effects
- Loose stools at high doses (less than with magnesium oxide/citrate)
Doses refer to elemental magnesium. This page summarizes research and is not medical advice.
Protocols
| Goal | Route | Dose | Frequency | Timing | Cycle | Evidence |
|---|---|---|---|---|---|---|
| Maintain or restore magnesium status Adults with low dietary magnesium Split into two doses if GI tolerance is an issue. | oral | 200–400 mg | 1×/day | with-food, evening | Continuous | human-rct |
| Subjective sleep support Adults with sleep complaints | oral | 200–400 mg | 1×/day | before-bed, with-food | Continuous | human-observational |
Evidence — Subjective sleep support
- paper supports The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial — Journal of Research in Medical Sciences · 2012
Claims & evidence
Effectively raises magnesium status in deficient or low-intake individuals.
Magnesium repletion positive human-rct
No indexed research or commentary linked yet.
May modestly improve subjective sleep quality, primarily in older or magnesium-deficient adults.
Sleep quality mixed human-observational
- paper mixed The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial — Journal of Research in Medical Sciences · 2012